Along the lines of our discussion regarding research ethics, Dr. William Schneider (Professor of History, Indiana University) provides an overview of the events and developments that led to the establishment of federal rules and regulations concerning research, including the Institutional Review Boards. This article addresses the Nuremberg Code, the Thalidomide Tragedy, the Declaration of Helsinki, the Henry Beecher article in the NEJM, the USPHS memo on review boards, and the Tuskegee Syphilis Study.
http://www.iupui.edu/~histwhs/G504.dir/irbhist.html
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